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Developing methods and software tools for understanding biological data and genomic applications

Boston

Service Description

Functional Genomics and Bioinformatics Core

Provides services to investigators looking to expand their research using state-of-the-art genomic applications. It utilizes next generation technologies and sequencing platforms to help identify the complex molecular mechanisms underlying human disease. Core staff can consult with researchers to ensure optimal experimental design on a case-by-case basis. Downstream or stand-alone data analysis pipelines are also offered to help researchers get the most from their datasets.

  • Consultation regarding experimental design and cost analysis
  • Sample quality assessment of DNA and RNA using the BioAnalyzer and Qubit assays
  • Next-generation sequencing library construction from RNA and DNA, including ChIP-Seq, ATAC-Seq, and MeDIP-Seq
  • Stand-alone sequencing services using the NextSeq 500 System
  • Basic data analysis, such as quality assessment and normalization, genomic alignment, differential expression/enrichment, GSEA, sample clustering, and motif enrichment
  • Advance data analysis on a consultative basis to maximize dataset potential

Have Questions? Contact Us.

Evan D. Rosen, MD, PhD, Director
Email • (617) 735-3222

Harvard Medical School

Service Description

Biostatistics Core

Expertise and advice for grant development, study design, data management, data collection, and data analysis. New statistical methods or novel applications of existing methods can be developed on an as-needed basis.

Have Questions? Contact Us.

Rebecca Betensky, PhD
655 Huntington Avenue
Building II Room 421
Boston, MA  02115
Email • Phone: (617) 726-6111
Fax: (617) 432-5619

University of Alabama at Birmingham

Service Description

Biostatistics Core

Statistical expertise for the design, management and analysis of nutrition-related research projects. Services include:

  • Secretarial/report generation
  • Data entry
  • Administrative support
  • Data management
  • Programming
  • Web system development
  • Statistical analysis

Have Questions? Contact Us.

Renee Desmond, PhD, Core Director
Email • Phone: (205) 934-3722