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Endogenous Oxytocin Levels in Relation to Food Intake, Menstrual Phase, and Age in Females

December 10, 2018

Summary: Though oxytocin is most commonly known for its role in uterine contraction during delivery, recent evidence demonstrates that it also has an anorexigenic effect.  Elizabeth Lawson and colleagues investigated the endogenous oxytocin response to food intake and its relationship to sensations of hunger and satiety in 55 normal weight, pre-menopausal females.  Oxytocin levels were higher in younger women and were lower in the early-mid follicular phase of the menstrual cycle.  Oxytocin levels decreased significantly during the first hour following a standardized meal, with a mean 20% reduction in levels compared to baseline.  Fasting levels of oxytocin were not associated … Read More »

Categories: Blogs, Featured News, News, Newsletters, Publications Tags: Harvard Medical School

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites

April 6, 2018

Summary: Intestinal microbes use various dietary components to produce energy and metabolites.  Many of these metabolites are absorbed into the host bloodstream where they may have harmful or beneficial effects on host metabolism.  To explore the effect of diet, genetics, and gut microbiome on plasma metabolites and insulin resistance, Fujisaka and colleagues exposed three different genetic strains of mice with varying propensities to obesity and diabetes to high fat diet (HFD) with or without concomitant antibiotic treatment (vancomycin or metronidazole).  HFD and antibiotic treatment substantially modified intestinal microbiome composition, and these effects varied by genetic strain.  Changes in the gut … Read More »

Categories: Featured News, News, Publications Tags: Harvard Medical School

UNC Nutrition Research Institute Seminar Series

March 29, 2018

Anorexia nervosa and the intestinal microbiota: do gut microbes influence weight gain and behavior during clinical re-nourishment? Date and Time: Thursday, April 12, 2018 12:00 PM – 1:00 PM Eastern Speaker: Ian Carroll, PhD (Assistant Professor, Department of Nutrition, University of North Carolina at Chapel Hill) Abstract: Abstract: Anorexia nervosa (AN), a psychiatric disorder characterized by extreme weight dysregulation commonly presents with comorbid anxiety. AN carries the highest mortality rate of all psychiatric illnesses and relapse is frequent. Therapeutic re-nourishment in AN is based primarily on clinical opinion and guidelines, and does not address the underlying etiology of the disorder. … Read More »

Categories: Blogs, Featured News, News Tags: University of North Carolina at Chapel Hill

Defining Precision Nutrition Symposium

February 6, 2018

Presented By UNC Nutrition Research Institute Kannapolis, North Carolina Symposium Focus the genetic, epigenetic, microbiome, and environmental sources of human metabolic variability how these variabilities are related to different requirements for, and responses to, nutrients methods used to assess the above Speakers Keynote: Jeremy Nicholson, PhD, Imperial College London Understanding Gene-Environment-Diet and Lifestyle Interactions in Human Health: A Molecular Phenomic Approach Lorraine Brennan, PhD, University College Dublin Metabotyping for Optimal Nutrition Ahmed El-Sohemy, PhD, University of  Toronto Genetic Testing for Personalized Nutrition Eric Martens, PhD, University of Michigan Molecular Mechanisms of Gut Bacteria and Metabolism of Glycans Susan Sumner, PhD, … Read More »

Categories: Blogs, Featured News, News Tags: University of North Carolina at Chapel Hill

UAB Nutrition Obesity Research Center – Social Media Update

January 19, 2018

New diet says limit hours spent eating instead of calories.

Categories: Blogs, Featured News, News Tags: University of Alabama at Birmingham

19th Annual Harvard Nutrition and Obesity Symposium

January 3, 2018

Save The Date! Registration opening soon in 2018! Stay Tuned.

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UNC Introduces New Core Merging Nutrition and Genetics

April 2, 2017

The University of North Carolina at Chapel Hill’s Nutrition Obesity Research Center (NORC) introduces the new Nutrigenetics and Nutrigenomics (NGx) Core. Located at the UNC Nutrition Research Institute (NRI) on the NC Research Campus in Kannapolis, the goal of the NGx Core is to assist investigators in conducting nutrigenetics and nutrigenomics studies that lead to a better understanding of the interaction between lifestyle and genetics on health and disease. “We want to help investigators realize that neither nutrition nor genetics should be studied in isolation,” explained Saroja Voruganti, PhD, NGx director and Assistant Professor of Nutrition at the NRI.  “Our … Read More »

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Genetic Risk Factors for Some Diseases Tied to Uric Acid

March 31, 2017

Viva La Familia Nutritional Study We once thought of circulating uric acid levels as mainly a biomarker of kidney disease (or a very rich diet), but research over the past decade suggests that higher than normal levels of uric acid can, in fact, be a cause of some cardiovascular or chronic kidney diseases. Uric acid levels are strongly influenced by a person’s genetics and diet, so understanding genetic risk factors will help to identify who needs to be extra careful about what he or she eats. This is the focus of the Voruganti laboratory at the NRI, which applies nutrigenetics … Read More »

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Daily Sugar-Sweetened Beverage Intake Alters Human Brain and Behavior, Study Finds

March 9, 2017

Research shows that consuming too much sugar over time contributes to weight gain and obesity-related conditions such as Type 2 diabetes and cardiovascular diseases. So why do we keep going back for more, even when the risks are clear? In a unique experiment, Kyle Burger, PhD, assistant professor of nutrition at the UNC Gillings School of Global Public Health and director of UNC’s Neuropsychology of Ingestive Behavior Laboratory, examined the behavioral responses of 20 healthy-weight individuals to a sugar-sweetened beverage and beverage logos after the individuals had a daily drink of that beverage for three weeks. Burger’s research, published online Feb. 8 … Read More »

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Physical Activity Good for Your Health, But What’s Happening Below the Surface?

January 5, 2017

New grant from National Institutes of Health will allow U-M researchers to focus on molecular changes that occur during and after exercise The University of Michigan was recently awarded $8.2 million from the National Institutes of Health to investigate the molecular changes that occur during and after physical activity. U-M is one of several centers throughout the United States to receive a grant from the NIH to participate in the Molecular Transducers of Physical Activity Consortium (MoTrPAC). The 6-year funding will begin this month and will allow U-M to establish the Michigan Chemical Analysis Site within the Consortium. The Consortium … Read More »

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