Category: News
Boston NORC Annual Symposium: COVID-19, Nutrition, and Obesity
Boston Nutrition Obesity Research Center Annual Symposium COVID-19, Nutrition, and Obesity Friday, December 4, 2020 8:45AM-12:00PM “The changing face of epidemiology during COVID-19. Lessons learned and opportunities for BNORC investigators” Jorge E. Chavarro, MD, ScD Associate Professor of Nutrition and Epidemiology, Department of Nutrition, Department of Epidemiology Harvard T.H. Chan School of Public Health “Does Vitamin D Reduce the Risk of COVID-19?” JoAnn E. Manson, MD, MPH, DrPH Chief, Division of Preventive Medicine, Brigham and Women’s Hospital, Professor of Medicine and the Michael and Lee Bell Professor of Women’s Health, Harvard Medical School, Professor in the Department of Epidemiology, Harvard … Read More »
Categories: Featured News, News Tags: Boston NORC1st Virtual Mid-Atlantic NORC Symposium
We are pleased to announce the 1st Virtual Mid-Atlantic NORC Symposium! Featuring: Sadaf Farooqi Sadaf Farooqi, FMedSci, is a Wellcome Trust Senior Research fellow in Clinical Science, Professor of Metabolism and Medicine at the University of Cambridge and a consultant physician at Addenbrooke’s Hospital in Cambridge, UK Date: Monday, November 9, 2020 Time: 9:00AM – 1:00PM EST Location: The program will be conducted remotely via Zoom. Please join the Mid-Atlantic Nutrition Obesity Research Center to share a day of learning and discussion with some of the brightest minds at UMB and JHU. The Symposium will begin with a Keynote presentation by … Read More »
Categories: Featured News, News Tags: Mid-Atlantic MarylandNORC Initiative to Advance the Careers of Researchers from Groups Underrepresented in Academia
The Nutrition Obesity Research Centers (NORCs), supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), host an initiative to identify the barriers and challenges to success of scientists from URiA groups and to identify actionable strategies to overcome these challenges. The goal is to provide specific recommendations to improve equity and inclusion for the NORCs, NORC-associated institutional leadership, and scientific societies such as the American Society for Nutrition (ASN) and The Obesity Society (TOS). Each event is from 11 a.m. – 1 p.m. (Central). And all sessions will be recorded and widely distributed through NORCs, NIDDK, … Read More »
Categories: Featured News, News, Press Release Tags: University of Alabama at BirminghamUNC-CH NORC July 2020 Newsletter
UNC-CH NORC July 2020 Newsletter
Categories: Featured News, News, Newsletters Tags: University of North Carolina at Chapel HillUNC-CH NORC April 2020 Newsletter
UNC-CH NORC April 2020 Newsletter
Categories: Featured News, News, Newsletters, Uncategorized Tags: University of North Carolina at Chapel HillUNC-CH NORC January 2020 Newsletter
UNC-CH NORC January 2020 Newsletter
Categories: Featured News, News, Newsletters Tags: University of North Carolina at Chapel HillThe muscle anabolic effect of protein ingestion during a hyperinsulinaemic euglycaemic clamp in middle‐aged women is not caused by leucine alone
Abstract It has been suggested that leucine is primarily responsible for the increase in muscle protein synthesis (MPS) after protein ingestion because leucine uniquely activates the mTOR‐p70S6K signalling cascade. We tested this hypothesis by measuring muscle p‐mTORSer2448, p‐p70S6KThr389 and p‐eIF2αSer51, as well as protein turnover (by stable isotope labelled amino acid tracer infusion in conjunction with leg arteriovenous blood and muscle tissue sampling), in 28 women who consumed either 0.45 g protein kg−1 fat‐free mass (containing 0.0513 g leucine kg−1 fat‐free mass) or a control drink (n = 14) or 0.0513 g leucine kg−1 fat‐free mass or a control drink (n = 14) during a hyperinsulinaemic‐euglycaemic clamp procedure … Read More »
Categories: Featured News, News, Publications Tags: Washington University St. LouisEffect of Progressive Weight Loss on Lactate Metabolism: a Randomized Controlled Trial
Abstract Objective Lactate is an intermediate of glucose metabolism that has been implicated in the pathogenesis of insulin resistance. This study evaluated the relationship between glucose kinetics and plasma lactate concentration ([LAC]) before and after manipulating insulin sensitivity by progressive weight loss. Methods Forty people with obesity (BMI=37.9±4.3 kg/m2) were randomized to weight maintenance (n=14) or weight loss (n=19). Subjects were studied before and after 6 months of weight maintenance and before and after 5%, 11% and 16% weight loss. A hyperinsulinemic-euglycemic clamp procedure in conjunction with [6,6-2H2]glucose tracer infusion was used to assess glucose kinetics. Results At baseline, fasting … Read More »
Categories: Featured News, News, Publications Tags: Washington University St. LouisDiurnal Variation in PDK4 Expression Is Associated With Plasma Free Fatty Acid Availability in People
Abstract Context Many biological pathways involved in regulating substrate metabolism display rhythmic oscillation patterns. In rodents, clock genes regulate circadian rhythms of metabolic genes and substrate metabolism. However, the interrelationships among substrate metabolism, metabolic genes, and clock genes have not been fully explored in people. Objective We tested the hypothesis that the diurnal expression pattern of pyruvate dehydrogenase kinase 4 (PDK4), a key metabolic enzyme involved in fuel switching between glucose and free fatty acids (FFAs), is associated with plasma FFA concentration and clock genes. Design and Methods We analyzed peripheral blood mononuclear cells (PBMCs), subcutaneous adipose tissue, and plasma … Read More »
Categories: Featured News, News, Publications Tags: Washington University St. LouisMichigan Nutrition Obesity Research Center Annual Symposium
The MNORC symposium provides a forum for intellectual exchange on topics related to obesity, nutrition and metabolomics among established investigators, junior faculty, students and other researchers at the University and surrounding area. Register here
Categories: News Tags: University of Michigan