Abstract Maximal exercise-associated oxidative capacity is strongly correlated with health and longevity in humans. Rats selectively bred for high running capacity (HCR) have improved metabolic health and are longer-lived than their low-capacity counterparts (LCR). Using metabolomic and proteomic profiling, we … Read more
Abstract Dietary phytosterols, plant sterols structurally similar to cholesterol, reduce intestinal cholesterol absorption and have many other potentially beneficial biological effects in humans. Due to limited information on phytosterol levels in foods, however, it is difficult to quantify habitual dietary … Read more
Abstract Dysregulation of thyroid hormones triiodothyronine and thyroxine (T3/T4) can impact metabolism, body composition, and development. Thus, it is critical to identify novel mechanisms that impact T3/T4 production. We found that type 2 taste receptors (TAS2Rs), which are activated by … Read more
CARE: Caring and Reaching for Health A Worksite Wellness Program for Child Care Staff UNC Gillings School of Global Public Health’s dynamic duo, Dianne Ward, Professor of Nutrition, and Laura Linnan, Professor of Health Behavior, have teamed up on a … Read more
Abstract Fatty acid synthase (FAS) is altered in metabolic disorders and cancer. Conventional FAS null mice die in utero so effects of whole body inhibition of lipogenesis following development are unknown. Inducible global knockout of FAS (iFASKO) in mice was … Read more
By now, many New Year’s resolutions of weight loss and healthy living have gone by the wayside thanks to a decadent Mardi Gras season, weak resolve or poor planning. And it’s no help that many festivities in south Louisiana revolve … Read more
Dr. Amanda Staiano’s surprising prescription for fighting adolescent obesity? Video games. Staiano completed a study, aptly named Klub Kinect, where teen girls played Xbox Kinect dance “exergames” as a way to get fit. Exergames are active video games that require … Read more
The University of Alabama at Birmingham’s NORC (UAB NORC) created a video to highlight their Center and core facilities. The UAB NORC shows its spirit of research, training and collaboration through this video presentation. Check it out!
Abstract The presence of large subcutaneous adipocytes in obesity has been proposed to be linked with insulin resistance and type 2 diabetes through the “adipose tissue expandability” hypothesis, which holds that large adipocytes have a limited capacity for expansion, forcing … Read more
Abstract Studies in adults indicate that dietary polyunsaturated fatty acid (PUFA) composition may play a role in development of adiposity. Because adipocyte quantity is established between late childhood and early adolescence, understanding the impact of PUFAs on weight gain during … Read more
