Despite the physical demands of firefighting, several recent studies have reported that greater than 75% of all current and new firefighter recruits are overweight and/or obese. Research also suggests that obesity had a significant impact on lower back muscular endurance. … Read more
Abstract The ciliopathies are a group of disorders caused by defects in genes associated with primary cilia. A subset of these are characterized by highly penetrant obesity, but the rates of diabetes differ significantly between them. In this study, Lodh … Read more
Abstract Vitamin D deficiency is associated with poor bone health and other adverse health outcomes; however, the associations are greatly attenuated in black vs white individuals. One possible explanation for this attenuation is different concentrations of bioavailable vitamin D metabolites … Read more
Abstract This study used quantitative magnetic resonance imaging (MRI) to test whether mediobasal hypothalamic (MBH) gliosis is associated with obesity and insulin resistance in humans. Sixty-seven participants underwent a fasting blood draw and MRI. Cases with radiologic evidence of MBH … Read more
THRIVE for Health Taking center stage this month is the wonderful Dr. Temitope Erinosho, Research Assistant Professor of Nutrition at UNC, and her innovative approach to obesity and cancer risk prevention in children from low-income families. Currently, she is developing … Read more
To stay healthy, kids might not have to press pause on their video game habits. Playing active video games that encourage dancing and low-intensity activity may actually help overweight and obese kids lose weight, according to researchers at Baton Rouge’s … Read more
Even though hundreds of study participants and numerous researchers have taken advantage of the Human Research Core in the UNC Nutrition Research Institute, it is one of the best kept secrets on the NC Research Campus (NCRC) in Kannapolis, NC. … Read more
Abstract Leptin administration restores euglycemia in rodents with severe insulin-deficient diabetes, and recent studies to explain this phenomenon have focused on the ability of leptin to normalize excessive hypothalamic-pituitary-adrenal (HPA) axis activity. Here, we employed a streptozotocin-induced rat model (STZ-DM) … Read more
Abstract The field of metabolomics continues to witness rapid growth driven by fundamental studies, methods development, and applications in a number of disciplines that include biomedical science, plant and nutrition sciences, drug development, energy and environmental sciences, toxicology, etc. NMR … Read more
Abstract Macrophages play a key role in the development of atherosclerosis. Murine noroviruses (MNV) are highly prevalent in research mouse colonies and infect macrophages and dendritic cells. Our laboratory found that MNV4 infection in mice lacking the LDL receptor alters … Read more
